Toothpaste showdown: stannous fluoride takes on bad breath
NCT ID NCT07425509
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a toothpaste with stannous fluoride is better at reducing bad breath than a standard fluoride toothpaste. 49 adults with halitosis brushed twice daily with each toothpaste in separate periods. Trained judges rated their breath odor at several time points. The goal was to see if the stannous fluoride formula provides better breath freshening.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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49 people
The number who actually took part.
- Started
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Sep 2024
- Finished
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Nov 2024
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults ≥18 years of age in good general health * Baseline odor intensity score ≥2 after approximately 12 hours of oral hygiene abstention * Intra-oral source of oral malodor * At least 18 natural teeth * Willing to comply with oral hygiene, dietary, and behavioral restrictions * Able to provide informed consent Exclusion Criteria: * Allergy to oral hygiene products * Pregnant or nursing * Serious medical conditions affecting oral malodor * Recent antibiotic or anti-inflammatory medication use * Smoker or user of smokeless tobacco * Advanced periodontal disease, frank caries, or significant oral pathology * Participation in another oral care study within 30 days
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Salus Research, Inc.
Fort Wayne, Indiana, 46825, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.