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New study aims to cut opioid overprescription after hand surgery

NCT ID NCT04044820

Symptom relief Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving patients a fixed, evidence-based number of opioid pills after hand or forearm surgery leads to fewer unused pills while still controlling pain. About 292 adults having elective outpatient hand surgery at Toronto Western Hospital will be randomly assigned to receive either the standardized prescription or usual care. The goal is to find a balance that avoids overprescription without sacrificing pain relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Oxycodone or Hydromorphone or Tylenol #3 (acetaminophen with codeine)
What this could lead to
If successful, this could lead to a standard, safer way to prescribe painkillers after hand surgery, reducing leftover pills and the risk of misuse.
What could go wrong
This is a small, single-center trial, so results may not apply everywhere. The focus is on prescription patterns, not a new treatment, so the impact is limited.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 292 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2019

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1\. Patients presenting to TWH for elective ambulatory hand and forearm surgery Exclusion Criteria: 1. Chronic opioid treatment, defined as more than 6 tablets of Oxycodone 5 mg per day (or equivalent) 2. Cognitive impairment or any other condition causing inability to use 'as required' medication for pain control 3. Language barrier preventing completion of patient diary 4. Patient refusal

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Conditions

The condition(s) this trial relates to.

opioid abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Opioid use

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Toronto Western Hospital

    RECRUITING

    Toronto, Ontario, M5T2S8, Canada

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