Can standing orders get more teens vaccinated against HPV?
NCT ID NCT06380114
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving nurses and doctors special training and allowing nurses to give the HPV vaccine without a doctor's order can increase vaccination rates. About 16,000 teens aged 9-17 from 40 medical practices will take part. The goal is to prevent HPV-related cancers by getting more young people vaccinated.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Standing orders (written protocols allowing nurses to vaccinate without a doctor's order) and communication training for healthcare providers
- What this could lead to
- If successful, this approach could significantly increase HPV vaccination rates and help prevent thousands of HPV-related cancers each year.
- What could go wrong
- This is a behavioral intervention, not a new vaccine. Success depends on real-world implementation, and results may vary across different practice settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 16,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2024
- Expected to finish
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May 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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9 to 17 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * active patient in AHP practice Exclusion Criteria: * patient belonging to a practice with \>80% UTD baseline HPV vaccination rate for ages 13-17 * patient belonging to a practice with \<20 11-12 year-olds eligible for an HPV dose
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Rochester Medical Center (URMC)
RECRUITINGRochester, New York, 14642, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- MRI scans may reveal which throat cancer patients need stronger treatment
- Could a single HPV shot match the standard regimen?
- Could Self-Sampling revolutionize cervical cancer screening?
- Texting parents could be key to curbing HPV-Related cancers
- Pocket-sized HIV test could bring same-day diagnosis to community clinics