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New depression pill shows promise in Mid-Stage trial

NCT ID NCT07226661

First seen Nov 10, 2025 · Last updated May 22, 2026 · Updated 31 times

Summary

This study tests whether a new drug called SPN-821 can help adults with major depression when added to their current antidepressant. About 230 people will receive either SPN-821 or a placebo for 29 days. The main goal is to see if the drug reduces depression symptoms more than placebo.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Collaborative Neuroscience Network

    RECRUITING

    Garden Grove, California, 92845, United States

Conditions

Explore the condition pages connected to this study.