New depression pill shows promise in Mid-Stage trial

NCT ID NCT07226661

First seen Nov 10, 2025 · Last updated May 09, 2026 · Updated 29 times

Summary

This study tests a new drug called SPN-821 in 230 adults with major depressive disorder who are already taking an antidepressant but still have symptoms. Participants will receive either SPN-821 or a placebo for about a month to see if the drug safely improves depression more than placebo. The main goal is to measure changes in depression scores using a standard rating scale.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Collaborative Neuroscience Network

    RECRUITING

    Garden Grove, California, 92845, United States

Conditions

Explore the condition pages connected to this study.