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Which anesthesia keeps weak hearts stable during surgery?

NCT ID NCT07752303

Disease control Sponsor: Sargodha Medical College Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 07, 2026 · Last updated Aug 11, 2026 · Updated 2 times

Summary

This trial compares two anesthesia methods—spinal (numbing only one leg) and general (full sleep)—for people with reduced heart function (ejection fraction 35-40%) undergoing lower limb surgery. The goal is to see which method keeps blood pressure more stable during the operation and reduces the need for extra medications. Participants are adults aged 18-70 with mild to moderate heart weakness, and the study tracks how well each method maintains hemodynamic stability.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Unilateral spinal anesthesia (bupivacaine) compared to general anesthesia
What this could lead to
If one method proves safer, it could guide anesthesia choices for heart patients, reducing complications during surgery.
What could go wrong
The trial is small and early, so results may not apply to all patients. Both anesthesia types carry risks, especially in those with weakened hearts.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 78 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with age 18-70year both male female having reduced ejection fraction 35 % -40%

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1\. Patient Age/Gender : 18-70 Years Male / Female. 2 Elective lower-limb surgery 3. Patients with reduced Ejection Fraction: rEF ( 35-40%) 4 ASA Class II-III Exclusion Criteria: 1. Emergency surgery. 2. Coagulopathy. 3. Spinal deformity or infection. 4. Drug allergy. 5. Severe pulmonary disease VI. Psychiatric and Neurological Illness. VII. BMI \> 35 kg/m² VIII. Allergic to local anaesthetic agents

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemodynamic (MAP) stability

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Dr Faisal Masood teaching Hospital sargodha

    Sargodha, Pakistan

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