Spinal zaps plus rehab may boost MS hand control
NCT ID NCT07152145
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether a non-invasive device that sends mild electrical currents to the spinal cord (tSCS) can improve upper limb function in people with multiple sclerosis. Sixty participants will receive either active stimulation or a sham (inactive) version during rehabilitation exercises twice a week for 12 weeks. The main goal is to see if the treatment improves hand speed and coordination, measured by the 9-Hole Peg Test.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- transcutaneous electrical spinal stimulation (tSCS) device
- What this could lead to
- If it works, this could offer a non-invasive way to improve hand and arm movement for people with MS, potentially making daily tasks easier.
- What could go wrong
- This is an early-stage trial with only 60 participants, and it uses sham stimulation as a comparison. The improvement may be small or not last long, and individual results can vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Oct 2025
An estimate. Start dates often move.
- Expected to finish
-
Dec 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 70 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 18 and 70 years. * Diagnosis of Multiple Sclerosis (according to revised McDonald criteria). * Upper limb dysfunction (9-Hole Peg Test score ≥ 20% slower than normative values). * Stable disease-modifying treatment for ≥ 6 months before enrollment. * Expanded Disability Status Scale (EDSS) score between 3.0 and 6.5. * Ability to provide informed consent. Exclusion Criteria: * Relapse or corticosteroid treatment within the last 3 months. * Severe spasticity of the upper limb (Modified Ashworth Scale \> 3). * Implanted electrical devices (pacemaker, spinal cord stimulator). * Epilepsy or uncontrolled seizures. * Severe psychiatric disorders or cognitive impairment interfering with study procedures. * Pregnant or breastfeeding women. * Participation in another interventional clinical trial within the last 3 months.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Multiple sclerosis are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Hospital del Mar
Barcelona, 08003, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can exercise rebuild muscle and balance in MS?
- Can diet ease the crushing fatigue of multiple sclerosis?
- One-Time CAR-T infusion tested against progressive MS
- Can PET scans reveal hidden brain inflammation in MS?
- Can a pill rebuild the Brain's insulation? MS trial puts remyelination to the test
- Migraines and tension headaches may be hidden companions to multiple sclerosis