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Can online speech therapy help those with Dementia-Related language loss?

NCT ID NCT06649084

Symptom relief Sponsor: University of Texas at Austin Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a speech-language telerehabilitation program for people with primary progressive aphasia (PPA), a dementia that slowly destroys language abilities. The program includes online therapy sessions and care partner training. Researchers will enroll 21 participants to see if the program is feasible, acceptable, and helpful for improving communication and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Multicomponent Lexical Retrieval Training (Multi-LRT) - a behavioral speech-language therapy program
What this could lead to
If successful, this could provide an evidence-based speech therapy program that helps people with PPA communicate better and improve their quality of life.
What could go wrong
This is a very small early-stage study (21 participants) focused on feasibility, not proof of effectiveness. Results may not apply to all PPA patients, and the therapy requires significant time commitment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 21 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2023

Expected to finish

Dec 2025

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Meets diagnostic criteria for Primary Progressive Aphasia (PPA; Gorno-Tempini et al., 2011) * Scores of 10 or higher on the Mini-Mental State Examination * Has a study partner who can consistently attend sessions Exclusion Criteria: * Other neurological or psychiatric diagnosis that may contribute to cognitive-linguistic deficits * Significant, uncorrected visual or hearing impairment that would interfere with participation * Score of less than 10 on the Mini-Mental State Examination * Prominent initial non-speech-language impairment (cognitive, behavioral, motoric)

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Conditions

The condition(s) this trial relates to.

aphasia frontotemporal dementia logopenic progressive aphasia Memory Disorders neurodegenerative disease primary progressive aphasia progressive non-fluent aphasia semantic dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aphasia Aphasia, progressive Logopenic progressive aphasia Nonfluent aphasia, progressive Primary progressive aphasia Semantic dementia Semantic memory disorder

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Texas

    Austin, Texas, 78712, United States

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