Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Stroke speech therapy: finding the right dose

NCT ID NCT04364854

Symptom relief Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested speech entrainment therapy (SET) in 80 people with non-fluent aphasia after a stroke. Participants practiced speaking along with an audio-visual computer program for 3, 4.5, or 6 weeks, or received no therapy. The goal was to find the best duration for lasting improvements in spontaneous speech.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Speech entrainment therapy (SET) - a computer program that helps practice fluent speech in real time
What this could lead to
If successful, this could point toward an optimal therapy duration to improve spontaneous speech in people with non-fluent aphasia after stroke.
What could go wrong
This is a small, early-phase study (80 participants) comparing different therapy lengths. Results may not apply to all types of aphasia or stroke survivors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

80 people

The number who actually took part.

Started

Aug 2020

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 81 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Aphasia as a result of a left hemisphere ischemic or hemorrhagic stroke (WAB-R Aphasia Quotient \<93.8). * Presence of left hemisphere stroke in clinical imaging (CT/MRI) and NIHSS * Participants must have spoken English as their primary language. * 21-81 years old * Pre-stroke modified Rankin Scale (mRS)= 2 or less * Post-stroke mRS= 4 or less. * At least 6 months post-stroke. * Non-fluent aphasia (WAB-R Comprehension score \>4 and WAB-R Fluency score \<6). * Technological compatibility (to be determined by clinical judgment of SLP) Exclusion Criteria * History of chronic neurological or psychiatric diseases (excluding migraines, depression, or post-stroke epilepsy). Self-reported history of learning disability. * Severe dysarthria (determined via SLP clinical judgment from spontaneous speech tasks on the ASRS 3.0). * Global aphasia. * History of right-hemisphere strokes or brain stem/cerebellar strokes with persistent deficits (as evidenced by MRI/CT and NIHSS). * Uncorrectable hearing as determined by the SLP's clinical judgment. * Uncorrectable vision. * Contraindications to MRI or inability to complete the MRI scanning session. * Women who are pregnant.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Aphasia are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

aphasia Aphasia, Broca progressive non-fluent aphasia stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aphasia Aphasia non fluent Stroke

Contacts and locations

Locations

  • Medical University of South Carolina

    Charleston, South Carolina, 29401, United States

  • University of South Carolina

    Columbia, South Carolina, 29208, United States

  • University of Utah

    Salt Lake City, Utah, 84112, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.