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Can a steroid gel stop Post-Surgery sore throat?

NCT ID NCT07256834

Symptom relief Sponsor: Jinnah Postgraduate Medical Centre Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a steroid gel (betamethasone) or a numbing gel (lidocaine) works better to prevent sore throat in adults who have a breathing tube during surgery. Sixty patients will be checked for sore throat 6 and 24 hours after their operation. The goal is to find a simple way to reduce discomfort after anesthesia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
betamethasone gel and lidocaine gel
What this could lead to
If betamethasone gel works better, it could offer a simple way to reduce sore throat after surgery with a breathing tube.
What could go wrong
This is a small, early-phase trial with only 60 people. Results may not apply to everyone, and side effects from the gels are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1/2

Runs two stages together: safety and dose first, then whether the treatment works.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Nov 2025

An estimate. Start dates often move.

Expected to finish

Dec 2025

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients aged 18-60 years 2. Either gender 3. ASA I to II 4. Patients planned for elective surgery under general anesthesia not lasting more than 4 hours. Exclusion Criteria: 1. Patients requiring more than 2 attempts for successful intubation 2. Patients undergoing surgeries of oral cavity or pharynx 3. Mallampati Score of 3 or 4 4. Patients with upper respiratory tract infection 5. Patients already taking steroids 6. Use of nasogastric tube perioperatively

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post operative sore throat at 6HRS and 24HRS after endotracheal intubation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.