Jinnah Postgraduate Medical Centre

This study tests whether a gel containing methotrexate, an immune-suppressing drug, can regrow hair in people with localized alopecia areata better than minoxidil spray. About 268 adults with less than 25% scalp hair loss will apply one of the two treatments twice daily for 24 we…

This study tests two prescription gels—metronidazole and clindamycin—to see which works better for moderate acne. Sixty adults aged 18 to 35 will apply the gel twice daily for 12 weeks. Doctors will check acne severity at the start and at weeks 4, 8, and 12 to measure improvement…

Researchers compare two ways to treat open contaminated wounds: vacuum-assisted closure (VAC) therapy and conventional saline-soaked dressings. Adults aged 15 to 60 with wounds 5 to 10 cm are randomly assigned to one method. The main question is which approach heals wounds faster…

The PRISM trial compares two radiation approaches after breast-conserving surgery for early-stage breast cancer. One approach treats only the area around the original tumor, while the other treats the whole breast. Both use the same short schedule of five radiation treatments. Re…

This trial tests whether a TAP block, an injection of local anesthetic into the abdominal wall, can reduce pain after laparoscopic gallbladder surgery. Researchers will compare 200 patients who receive the block with those who do not, measuring pain scores, painkiller use, and ho…

This study tests whether a medicated cream called crisaborole works better than a placebo cream for people with mild to moderate eczema. About 270 people aged 12 to 50 will apply the cream twice daily for four weeks. The goal is to see if the cream can clear or nearly clear the e…

This study tests whether a steroid gel (betamethasone) or a numbing gel (lidocaine) works better to prevent sore throat in adults who have a breathing tube during surgery. Sixty patients will be checked for sore throat 6 and 24 hours after their operation. The goal is to find a s…