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A cream that could loosen stiff, painful joints – trial puts it to the test

NCT ID NCT05799391

Symptom relief Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial tests whether a soothing cream jel can improve range of motion and reduce chronic pain in the shoulder or elbow. About 70 adults with long-term upper-limb pain will apply either the active cream or a placebo. Researchers will measure changes in how far the joint can move and how much pain people feel.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a soothing cream jel applied to the skin
What this could lead to
If it works, this could offer a simple, non-drug option for easing chronic upper-limb pain and improving mobility.
What could go wrong
This is a small, early-phase trial, so results may not apply widely. The cream may work no better than a placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

70 people

The number who actually took part.

Started

Jul 2023

Finished

May 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18-60; 2. Participates in regular physical activity, at least once a week for 30 minutes; 3. Chronic pain in the shoulder or elbow longer than 3 months; 4. 11-items Numeric pain rating scale ≥4; and 5. Willing to provide written informed consent. Exclusion Criteria: 1. The patient had received previous physiotherapy, acupuncture, Tui Na massage, or bone-setting treatment for distal upper limb pain within the past 2 weeks; 2. The pain was due to a fracture or known complex regional pain syndrome. 3. History of upper limb surgery; 4. Known severe medical conditions (e.g. rheumatoid arthritis, osteoporosis, cardiac, renal, hepatic, hematological diseases, vertigo, seizure, infection, malignancy, neurological impairment); 5. Concomitant drugs of NSAIDs, any kind of painkillers, or anti-inflammatory drugs 15 days prior to randomization; 6. Known impaired hematological profile and liver / renal function; 7. Known allergic history to any topical cream; 8. Known pregnant or lactating; or 9. Unable to complete questionnaires

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Upper extremity problem

Contacts and locations

Locations

  • Hong Kong Institute of Integrative Medicine

    Hong Kong, Hong Kong

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