Fat vs fibrin: which boosts dental implant success?
NCT ID NCT07562334
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether using a small piece of fat from the cheek (buccal pad of fat) works as well as a blood-derived gel (platelet-rich fibrin) to cover special dental implants in the upper jaw. About 24 adults with severe bone loss in the upper back jaw will receive one of the two treatments. The goal is to see which method leads to thicker gum tissue and fewer complications like fractures or infections.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 24 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients with severely atrophic edentulous upper arch (Cawood class IV, V, VI) that could not be restored by other type of treatment 2. Patients who had at least 8-12 mm vertical bone height in anterior maxilla to allow installation of 2 conventional implants. 3. Lacking posterior maxillary bone support due to significant sinus pneumatization 4. Good systemic health (ASA score I-II) 5. Highly motivated patients Exclusion Criteria: 1. Patient not willing to give his/her informed consent. 2. Patients with systemic disease that did not permit the surgical procedure (including general anesthesia). 3. Patients with uncontrolled diabetes or under bisphosphonate therapy. 4. Heavy smoker. (\> 20 cigarettes daily) 5. Patient with psychiatric problems, severe bruxism or other parafunctional habits. 6. Acute sinusitis. 7. Malignancy or pathology in Maxilla or Zygoma.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Cairo university, Faculty of dentistry
RECRUITINGCairo, Cairo Governorate, 11562, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New dental implant cap may improve gum healing
- New study tests better gum coverage for dental implants in fragile jaws
- Gum graft boosts dental implant outcomes in small study
- Gum graft boosts implant infection fight
- Dental implant study tests best graft placement for better healing