Could a food additive help fight stomach cancer? new trial explores
NCT ID NCT07615907
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding sodium propionate, a common food preservative, to standard immunotherapy and chemotherapy can improve tumor shrinkage in people with advanced stomach cancer. About 20 adults with inoperable gastric cancer will be randomly assigned to receive either sodium propionate capsules or a placebo alongside their regular treatment for 12 weeks. The main goal is to see if the combination leads to better tumor responses.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Subjects voluntarily participated in the trial and signed the informed consent form; * Aged ≥ 18 years and \< 80 years, regardless of gender; * Stable vital signs; * Patients with gastric adenocarcinoma confirmed by gastroscopic biopsy; * Tumors judged as unresectable by attending physicians; * Receiving anti-PD-1 therapy combined with chemotherapy as first-line treatment; * No history of allergic diseases and non-allergic constitution; * No history of drug abuse; * Non-pregnant and non-lactating females (applicable to male subjects as well); * No participation in any drug clinical trial (including investigational drugs of this trial) within 3 months prior to enrollment. Exclusion Criteria: * Failure to meet the inclusion criteria, or individuals deemed inappropriate for trial participation by investigators; * Concurrent primary malignant tumors at other sites; * Poor general condition, severe infection, respiratory insufficiency, or other conditions leading to inability to cooperate with the trial; * Patients with mental disorders, consciousness disturbance, or poor treatment compliance; * Suspected or confirmed history of drug abuse; * Immunodeficiency, or long-term use of immunosuppressants and glucocorticoids; * Pregnant or lactating women; * Sponsors, investigators directly involved in this trial, and their immediate family members; * Individuals unsuitable for enrollment for any reason as judged by the investigator.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Xinying Wang
Nanjing, Jiangsu, 210002, China
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