Root canal relief? study tests weaker bleach for less pain
NCT ID NCT07618182
First seen Jun 02, 2026 · Last updated Jun 23, 2026 · Updated 4 times
Summary
This study compares two strengths of sodium hypochlorite (a disinfectant used during root canals) to see which causes less pain afterward. 116 adults needing a root canal will be randomly assigned to receive either a 2.5% or 5.25% solution. Pain levels will be measured at 6, 12, 24, and 48 hours after treatment using a simple pain scale.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
sodium hypochlorite
What this could lead to
If it works, this could show that a lower concentration of sodium hypochlorite reduces pain after root canal treatment while still cleaning the tooth effectively.
What could go wrong
This is a small, early-stage trial with only 116 participants. The results may not apply to everyone, and the difference in pain between the two concentrations might be small or not meaningful.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.