Can a 3D-Printed tooth preserve your gum line after extraction?
NCT ID NCT07748871
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This trial tests two methods for sealing the socket left after a tooth is removed, with the goal of preserving the gum and bone for a future replacement. One method uses a fixed, 3D-printed temporary tooth that supports the gum tissue, while the other uses a removable plastic guard with a collagen seal. Both groups receive a bone graft to maintain the ridge. The study measures how well the gum height between teeth is maintained at 5 months, using digital scans.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Fixed ovate pontic provisional restoration (3D-printed) versus removable Essix provisional with collagen matrix seal, both with socket grafting using Bio-Oss Collagen (deproteinized bovine bone mineral with collagen)
- What this could lead to
- If successful, this could point to a better way to preserve gum and bone shape after tooth extraction, potentially improving the fit and look of future dental implants.
- What could go wrong
- This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. The fixed provisional may cause discomfort or require more maintenance, and the outcome depends on individual healing.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Feb 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years or older * ASA physical status I or II * Requiring a single non-molar tooth extraction (incisor, canine, or premolar) in the maxilla or mandible, with planned tooth replacement * Extraction site bounded by natural, periodontally stable adjacent teeth * Intact alveolar socket upon extraction, or no more than one bony wall (facial, palatal, or lingual) presenting a dehiscence extending less than 50% of the total bony wall height * Willingness and ability to comply with the follow-up protocol * Ability to give informed consent, as documented by signature Exclusion Criteria: * Current smokers, or former smokers who quit less than 6 months before extraction * Uncontrolled diabetes mellitus (HbA1c \> 7.0%) * Clinical attachment loss ≥ 2 mm at the extraction site * Active or recent chemotherapy, or history of head and neck radiotherapy * Current or previous bisphosphonate therapy within the past 10 years * Immunosuppressive medication * Active oral or systemic acute infection * Severe hematologic disorder, hepatic or renal failure, or any clinically relevant bleeding disorder or anticoagulant medication that cannot be safely managed for the planned surgical procedure * Pregnancy or lactation * Known allergy or hypersensitivity to any of the study materials, including bovine-derived bone substitute, porcine-derived collagen matrix, or collagen-containing biomaterials * Any other disease or medication that may compromise normal wound healing * Inability to follow the study procedures (e.g., insufficient language comprehension, cognitive impairment, psychological disorder, or dementia) * Known or suspected non-compliance * Participation in another clinical trial that may interfere with the present study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Bern, Department of Reconstructive Dentistry and Gerodontology
Bern, Canton of Bern, 3010, Switzerland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Stem cell signals could help rebuild jawbone for dental implants
- Your pulled tooth could rebuild your jaw
- The race to save jawbone: four socket techniques go head to head
- Can a custom healing cap preserve gum and bone after tooth extraction?
- Can a Single-Step dental implant restore smiles in the very old?
- Your extracted tooth may become the next bone graft