Can a simple tool reduce pancreatitis risk during ERCP?
NCT ID NCT05336630
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether using forceps to help guide a tube into the bile duct during an ERCP procedure makes the process easier and reduces the chance of pancreatitis afterward. 152 patients were randomly assigned to either standard cannulation or forceps-assisted cannulation. The goal was to see if the forceps group had fewer difficult cannulations and less post-ERCP pancreatitis.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Forceps (medical device used to grab tissue and assist cannulation during ERCP)
- What this could lead to
- If successful, this technique could make ERCP procedures easier and safer, potentially lowering the risk of post-procedure pancreatitis.
- What could go wrong
- This is a small, completed study with 152 participants. The forceps technique may not reduce pancreatitis risk significantly, and results may not apply to all patients or settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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152 people
The number who actually took part.
- Started
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May 2022
- Finished
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Oct 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: PRIMARY INCLUSION CRITERIA: * Patient consent * ERCP done on native papilla SECONDARY INCLUSION CRITERIA: * Papilla in a diverticulum * Papilla on rim of a diverticulum * Difficult cannulation (5 attempts, 5 minutes, or 2 unintended PD wire passages) * Redundant tissue overlying papilla * Type 2, 3, or 4 papilla Exclusion Criteria: * Prior ampullectomy * Known pregnancy, positive test, breastfeeding * Clinical contraindication to ERCP * Metal allergy * Prior sphincterotomy * Inability to follow protocol * \<18 years old * Enrolled in another ERCP study * Biliary/PD stent in place
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dartmouth Health
Lebanon, New Hampshire, 03756, United States
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