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Fish extract may ease period pain by fighting inflammation

NCT ID NCT07677462

Symptom relief Sponsor: Universitas Sriwijaya Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study investigates whether an extract from snakehead fish (Ophiocephalus striatus) can reduce menstrual pain in teenage girls with primary dysmenorrhea—cramps without an underlying disease. The trial gives participants either the fish extract or a placebo for 14 days before their period, then measures pain levels and inflammatory markers in the blood. The goal is to see if the extract's anti-inflammatory properties can offer a natural way to ease period pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ophiocephalus striatus (snakehead fish) extract
What this could lead to
If it works, this could offer a natural, accessible option for managing menstrual pain by reducing inflammation.
What could go wrong
This is a small, early-stage trial with only 40 participants. Results may not apply to everyone, and more research is needed to confirm benefits and safety.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Mar 2023

Finished

Jun 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

10 to 19 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adolescent girls aged 10-19 years who are diagnosed with primary dysmenorrhea with regular menstrual cycles. * Menstrual pain occurs at least 1 year after menarche. * Willing to participate in the study and approved by parents by signing an informed consent form. Exclusion Criteria: * Has a history of or is currently suffering from gynecological diseases obtained from the results of anamnesis that has been confirmed by an obstetrician-gynecologist. * Suffering from acute or chronic diseases, for example: fever, ARI, sore throat, toothache, ear inflammation, autoimmune, and systemic lupus erythematosus (SLE), rheumatoid arthritis. * Consuming corticosteroid drugs in the long term (for example: bethamethasone, dexamethasone, methylprednisolone, prednisolone, prednisone, triamcinolones, hydrocortisone, and cortisone) * History of hypersensitivity to Ophiocephalus striatus.

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Conditions

The condition(s) this trial relates to.

primary dysmenorrhea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Primary dysmenorrhea (PD)

Contacts and locations

Locations

  • Faculty of Medicine, Universitas Sriwijaya

    Palembang, South Sumatra, 30114, Indonesia

More trials for these conditions

Other studies related to the condition(s) this trial covers.