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Just one cigarette changes your eyes in minutes, study finds

NCT ID NCT07580040

Knowledge-focused Sponsor: Istanbul University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at what happens to the front part of the eye (the cornea) right after smoking a cigarette. Researchers will measure changes in corneal thickness and clarity in 90 healthy adults, comparing smokers to non-smokers. The goal is to understand if smoking causes immediate, measurable effects on eye structure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Healthy adult smokers and non-smokers aged 18 to 60 years are planned to be included in this single-center study.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy adults aged 18 to 60 years * Current smokers in the smoking group * Never-smokers in the control group * Willing and able to undergo ophthalmic examination and Pentacam AXL measurements Exclusion Criteria: * History of ocular surgery or ocular trauma * Presence of corneal disease, retinal disease, or ocular surface disorder * Clinically significant dry eye disease * Contact lens use within the last 2 weeks * Use of medications that may affect the ocular surface or pupillary dynamics, including anticholinergics or sympathomimetics * Systemic diseases such as diabetes mellitus or hypertension * Former smoking history in the control group * Use of electronic cigarettes or other tobacco products * Inability to cooperate adequately for accurate measurement

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Conditions

The condition(s) this trial relates to.

Cigarette Smoking corneal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anterior eye segment measurements CORNEA Smoking, cigarette

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Istanbul University, Istanbul Faculty of Medicine

    RECRUITING

    Istanbul, 34093, Turkey (Türkiye)

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