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New program aims to help hospitalized smokers kick the habit for good

NCT ID NCT05733767

Disease control Sponsor: Baystate Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a personalized smoking cessation program for smokers admitted to the hospital with heart or lung disease. Participants receive tailored medication, counseling, and text message support to help them quit and stay smoke-free. The goal is to see if this approach leads to more people using effective quit-smoking medicines and actually stopping smoking long-term.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
smoking cessation pharmacotherapy (varenicline or nicotine patch plus lozenge/gum/inhaler)
What this could lead to
If successful, this could provide a proven, cost-effective way to help hospitalized smokers with heart or lung disease quit for good, reducing relapse and improving health outcomes.
What could go wrong
This is a Phase 2 trial with 424 participants at one hospital, so results may not apply to all smokers. The program relies on patient motivation and follow-up, which may be challenging.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 424 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2022

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Admitted to Baystate Medical Center in Springfield, MA with a cardiac or pulmonary disease diagnosis will be eligible to participate in this trial. * Patients who smoke cigarettes * Speak English We will include any patients with the following diagnoses or procedures from Baystate Medical Center in Springfield, MA: * myocardial infarction * coronary artery bypass grafting surgery * heart valve surgery * percutaneous coronary intervention (PCI) * acute coronary syndrome * heart failure * chronic obstructive pulmonary disease (COPD) * asthma exacerbation. Exclusion Criteria: * We will exclude pregnant or nursing women, patients with current suicidal ideation, planned discharge to hospice or expected survival \<6 months, or concurrent use of daily smoked marijuana, because this can increase exhaled carbon monoxide levels, which would confound biochemical confirmation.

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Conditions

The condition(s) this trial relates to.

acute asthma acute coronary syndrome chronic obstructive pulmonary disease cor pulmonale heart failure myocardial infarction Smoking Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiopulmonary disease Inpatient Smoking cessation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Baystate Medical Center

    RECRUITING

    Springfield, Massachusetts, 01199, United States

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