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Simple dental exam before heart surgery may prevent deadly infections

NCT ID NCT07511673

First seen Apr 25, 2026 · Last updated Jun 21, 2026 · Updated 13 times

Summary

This study is testing whether having a dental checkup before heart valve surgery can prevent serious complications like infection of the heart lining, repeat surgery, or death. About 1,300 adults scheduled for valve surgery will be randomly assigned to either get a dental screening or not. Researchers will then track their health for two years to see if the screening group has fewer problems.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Karolinska University Hospital

    NOT_YET_RECRUITING

    Stockholm, Sweden

    Contact Phone: •••-•••-••••

  • Linköping University Hospital

    NOT_YET_RECRUITING

    Linköping, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sahlgrenska University Hospital

    NOT_YET_RECRUITING

    Gothenburg, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Skane University Hospital

    RECRUITING

    Lund, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Örebro University Hospital

    NOT_YET_RECRUITING

    Örebro, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

preoperative dental screening

What this could lead to

If it works, this could show that a simple dental exam before heart valve surgery reduces the risk of life-threatening infections and the need for repeat surgery.

What could go wrong

This is a large trial, but it's still possible that dental screening won't significantly improve outcomes. The study is open-label, so both patients and doctors know which group they're in, which could introduce bias.

Conditions

The condition(s) this trial relates to.

endocarditis heart valve disorder infective endocarditis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.