Smartphone Check-Ins could save transplanted kidneys
NCT ID NCT05897047
First seen Jun 27, 2026 · Last updated Sep 02, 2026 · Updated 2 times
Summary
This study tests whether extra telemedicine support (using a smartphone or tablet) can help kidney transplant recipients better manage their health and keep their new kidney working longer. About 384 people who received a kidney transplant in the last year will be split into two groups: one gets standard follow-up care, the other gets additional remote monitoring and check-ins. The goal is to see if telemedicine improves medication adherence, reduces hospital visits, and prevents kidney rejection or failure.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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391 people
The number who actually took part.
- Started
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May 2023
- Finished
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Jul 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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1 year to 99 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Kidney transplantation within last 12 months * Treatment with tacrolimus * Routine aftercare planned at KTC * Ability to use a smartphone or tablet or with help of someone close by * For children \< 12 years parents have to take over the use of the smartphone * Patients who are willing and able to participate in the study and from whom written informed consent has been obtained prior to study participation or pediatric patients with parenteral consent * Ability to communicate in German or English * Adequate and stable renal function (eGFR \> 30 ml/min, Proteinuria \< 1g/g creatinine) eGFR will be determined according to CKD-EPI for adults \[81\] or Schwartz formula for children \[82\] Exclusion Criteria: * Patient with mental dysfunction or inability to comply with the study protocol or pediatric patients whose parents cannot comply with the study protocol * Any significant diseases or clinically significant findings, including psychiatric and behavioral problems, medical history and/or physical examination findings that would in the opinion of the investigator preclude the patient from participating in the study * History of alcohol or drug abuse with less than 6 months of sobriety * Participation in any other interventional clinical trial less than 1 month before participation in this study * Patients who have been institutionalized by official or court order * Patients with a combined kidney transplant or multi-organ recipients (other solid organ (e.g. pancreas) or bone marrow) * Presence of DSA with MFI \> 1000 at time of transplantation * Recurrence of underlying kidney disease (e.g. focal segmental glomerulosclerosis (FSGS) or atypical hemolytic uremic syndrome (aHUS) * Patient with active malignancy post-transplant with the exception of local, non-invasive, fully excised, cutaneous basal cell carcinoma, cutaneous squamous cell carcinoma, or cervical carcinoma in situ * Patients with clinically symptomatic congestive heart failure (CHF) or symptomatic coronary artery disease * Patients with documented (either by serology and/or nuclear acid testing (NAT) clinically active infections (e.g. with a known hepatitis B (HBV), hepatitis C (HCV), HIV, CMV or BK virus infection).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Charité Universitätsmedizin Berlin
Berlin, Bavaria, 10117, Germany
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University Hospital Essen
Essen, Germany
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Other studies related to the condition(s) this trial covers.
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