Which pump mode wins for exercise? new study tests SmartGuard vs temp target
NCT ID NCT06728423
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at 14 people with type 1 diabetes who use the MiniMed 780G insulin pump. They will do a supervised strength training session twice, once with the pump in SmartGuard mode and once with a temporary target setting. The goal is to see which setting keeps blood sugar in a safe range and prevents low blood sugar during and after exercise.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 14 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2025
An estimate. Start dates often move.
- Expected to finish
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Nov 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosis of type 1 diabetes ≥ 1 year ago * AHCL users (Minimed 780G) with integrated continuous glucose monitoring * Use of the device for at least the last 3 months * Physically active (PA≥1): At least one weekly physical exercise session in the last 6 months. Exclusion Criteria: * Pregnancy * Physical or mental inability to exercise * Contraindication to performing Valsalva maneuvers * History of osteoarticular disease that prevents exercise * History of tendinopathies that cause pain or limitation * History of coronary artery disease * Diabetic ketoacidosis or severe hypoglycemia in the last month * Evidence of autonomic failure (Unnoticed hypoglycemia given by Clarke 3 or more points Appendix 1) I am concerned because now that I am on a pump, this indication is common as support for the insulin pump. * Use of beta-blockers or glucocorticoids * Peripheral arterial disease * Severe proliferative diabetic retinopathy or non-proliferative diabetic retinopathy * Severe peripheral neuropathy * Stage 5 chronic kidney disease on renal replacement therapy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital Universitario San Ignacio.
Bogotá, Bogota D.C., 111021, Colombia
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