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Smart wristband may spot thyroid drug imbalances before blood tests do

NCT ID NCT07733375

Knowledge-focused Sponsor: Yeditepe University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This study tests whether a smart wristband that records nighttime heart rate and rhythm can tell if the dose of thyroid medication (levothyroxine) is too high or too low after total thyroid removal. Forty adults will wear the wristband for the first month after surgery, and the device's readings will be compared with standard thyroid blood tests taken at the one-month checkup. The goal is to see if wearable data can flag dosing problems earlier than routine lab work.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a smart wristband (Xiaomi Smart Band 10) that records nighttime heart rate and rhythm
What this could lead to
If it works, this could point toward a simpler, non-invasive way to monitor thyroid medication dosing after thyroid removal, potentially reducing the need for frequent blood tests.
What could go wrong
This is a small, early observational study. The smart wristband may not be accurate enough to replace standard blood tests, and results may not apply to other wearable devices or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adults undergoing total thyroidectomy who require postoperative levothyroxine replacement therapy. Participants will be recruited from the Department of General Surgery at Yeditepe University Koşuyolu Hospital. All participants will receive standard postoperative care and wear a smart wristband during the first postoperative month for continuous monitoring of nighttime heart rate and heart rhythm.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Age 18 years or older. Undergoing total thyroidectomy at the Department of General Surgery, Yeditepe University Faculty of Medicine Hospital. Initiation of levothyroxine as part of routine postoperative clinical care. Willing and able to attend the routine 1-month postoperative thyroid function test follow-up visit. Willing and able to wear the Xiaomi Smart Band 10 throughout the study period. Able to provide written informed consent. Exclusion Criteria: History of cardiac arrhythmia. Current use of beta-blockers or other antiarrhythmic medications that may affect heart rate. History of heart failure or advanced cardiovascular disease. Diagnosed sleep disorders that may interfere with nighttime heart rate measurements. Pregnancy. Inability or unwillingness to wear the smart wristband as required. Missing clinical or laboratory data required for outcome assessment. Refusal to participate or withdrawal of informed consent.

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Conditions

The condition(s) this trial relates to.

hyperthyroidism hypothyroidism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hyperthyroidism Hypothyroidism Total thyroidectomy

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Yeditepe University Koşuyolu Hospital

    RECRUITING

    Istanbul, Kadıköy, 34718, Turkey (Türkiye)

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