Can a simple supplement fix sleep after a concussion?
NCT ID NCT04603443
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 38 times
Summary
This study tested whether taking branched-chain amino acids (BCAAs) can improve sleep and thinking in veterans who have had a mild traumatic brain injury. 160 veterans were randomly assigned to receive different doses of BCAAs or a placebo for 12 weeks. The main goal was to see if the study procedures were practical and if veterans would stick with the treatment, not yet to prove it works.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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VA Portland Health Care System, Portland, OR
Portland, Oregon, 97207-2964, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Branched-chain amino acids (BCAAs)
What this could lead to
If it works, this could point toward a simple dietary supplement to help veterans with mild TBI sleep better and think more clearly.
What could go wrong
This was a small, early-stage trial focused on feasibility, not proof of effectiveness. The results may not show clear benefits, and side effects like stomach upset are possible.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.