Could a simple head tilt prevent oxygen drops after endoscopy?
NCT ID NCT07587970
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares three recovery positions—side-lying with head up, lying on back with head up, and standard side-lying—to see which best prevents low oxygen levels after painless stomach and colon exams. Over 1,600 adults will be randomly assigned to one position. The goal is to find a simple, non-invasive way to improve safety during recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- positioning procedure (lateral decubitus head-up or supine head-up)
- What this could lead to
- If it works, this could give doctors a simple, no-cost way to prevent oxygen drops after routine endoscopy.
- What could go wrong
- This is a positioning study, not a drug trial. The benefit may be small or not apply to all patients. Results are still being collected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,617 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age ≥ 18 years. 2. Both sexes. 3. American Society of Anesthesiologists (ASA) physical status classification I-III. 4. Scheduled for combined painless esophagogastroduodenoscopy/colonoscopy or either of the two procedures. 5. Ability to understand the study protocol and provide written informed consent. 6. A broad set of inclusion criteria was adopted to enroll a patient population that better reflects routine clinical practice. The study aimed to enhance the generalizability of the findings by including patients with various comorbidities, such as preprocedural hypoxemia (room-air SpO₂ ≤ 90%), history of pulmonary surgery, obstructive sleep apnea (OSA), and other pulmonary conditions (including asthma, COPD, chronic bronchitis, emphysema, and pulmonary bullae). Exclusion Criteria: 1. Severe cardiovascular or cerebrovascular diseases. 2. Pregnant patients. 3. History of hypersensitivity to ciprofol. Withdrawal Criteria: 1. Endotracheal intubation required during the procedure. 2. Voluntary withdrawal requested by the patient or their legal representative.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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General hospital of Ningxia medical university, Yinchuan, Ningxia
RECRUITINGYinchuan, Ningxia, 750001, China
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