New monitoring method may keep seniors breathing easier after surgery
NCT ID NCT07652385
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether adding a special carbon dioxide monitor through the nose can reduce dangerous drops in oxygen levels in elderly patients (ages 65-80) waking up from anesthesia after laparoscopic abdominal surgery. About 324 participants will be randomly assigned to standard care or standard care plus this extra monitoring. The goal is to see if the extra monitor helps prevent low oxygen episodes and improves safety during recovery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 324 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 65-80 years; * ASA physical status I-III; * BMI 18-30 kg/m²; * Participants scheduled for elective laparoscopic surgery under general anesthesia with endotracheal intubation; * Willing to participate in the study and provide written informed consent Exclusion Criteria: * Patients with nasal bleeding, nasal mucosal injury, nasal cavity occupancy, or other conditions that preclude transnasal carbon dioxide monitoring; * Patients undergoing emergency surgery; * Participants requiring postoperative assisted ventilation via endotracheal intubation or tracheostomy; * Presence of any disease or condition that may cause abnormal end-tidal carbon dioxide waveforms or abnormal baseline pulse oximetry (e.g., congenital heart disease or chronic lung disease); * Severe cardiac insufficiency (≤4 Metabolic Equivalents \[MetS\]); * Severe renal insufficiency (acute kidney injury \[AKI\] or chronic kidney disease \[CKD\] stage 4 or higher); * Severe hepatic insufficiency (Child-Pugh class C or worse); * Allergy to study medications; * Daily alcohol intake ≥60 grams; * History of psychiatric disorders such as depression, severe central nervous system depression, Parkinson's disease, basal ganglion lesions, schizophrenia, epilepsy, Alzheimer's disease; * Participation in another related clinical study within the past 3 months.
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As listed by the trial registrant
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How to take part
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The official record
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A doctor treating you
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More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a handheld device match standard monitors for measuring exhaled CO2?
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- Can a steady drip of local anesthetic speed recovery after open-heart surgery?
- Hidden mental health burden before surgery in seniors?