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Could a Blood-Derived patch replace costly sealants in brain surgery?

NCT ID NCT03910374

First seen May 25, 2026 · Last updated Jun 12, 2026 · Updated 5 times

Summary

This study tested whether a membrane made from a patient's own blood (L-PRF) can seal the skull base after sinus surgery as well as standard materials. 220 adults with tumors near the pituitary gland took part. The goal was to see if the natural membrane prevents spinal fluid leaks just as effectively and at a lower cost.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AZ Sint-Jan

    Bruges, 8000, Belgium

  • Fundació Clínic Per A La Recerca Biomèdica

    Barcelona, 08036, Spain

  • UZ Leuven

    Leuven, 3000, Belgium

Conditions

The condition(s) this trial relates to.

craniosynostosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.