Reading the Body's stress signal from the skin
NCT ID NCT03243448
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This study is testing a new, non-invasive way to measure the body's sympathetic nervous system — the part that controls the 'fight-or-flight' response. Researchers will record nerve activity from the skin of about 1,000 people, including healthy volunteers and those with conditions like high blood pressure, heart failure, or sleep apnea. The goal is to see if this simple skin recording can reliably estimate sympathetic tone, which could make it easier for doctors to monitor and understand these conditions.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- non-invasive skin sympathetic nerve activity recording
- What this could lead to
- If successful, this could provide a simple, non-invasive way to monitor the body's stress response, potentially helping doctors understand and manage conditions linked to sympathetic overactivity.
- What could go wrong
- This is an early-stage method validation study, not a treatment trial. The technique may not prove reliable or practical in everyday clinical settings, and it does not test any therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2016
- Expected to finish
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Jul 2032
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The subjects who are eligible to the inclusion criteria and admitted to the investigators' ward, visited the investigators' outpatient clinic or health checkup center will be enrolled in the investigators' study.
- Ages
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20 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Sympathetic hyperactivity diseases included: hypertension, heart failure atherosclerotic diseases, arrhythmias, cardiomyopathy, pulmonary hypertension, chronic obstructive pulmonary disease, sleep apnea, pulmonary embolism, hepatitis, liver cirrhosis, hepatopulmonary syndrome, hepatorenal syndrome, renal failure, nephritis, irritable bowel syndrome. * Healthy Volunteers Exclusion Criteria: * Pregnant
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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