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Ancient chewing stick could rival toothbrush for gum health

NCT ID NCT07702383

Disease control Sponsor: National University of Malaysia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Jul 16, 2026 · Updated 2 times

Summary

This trial compares a standardized siwak (chewing stick) oral hygiene program to conventional toothbrushing for improving gum health in young adults with gingivitis. Participants are dental students aged 18–24 who will follow either the siwak module or toothbrushing for 21 days. The study measures plaque, gum inflammation, and bleeding, as well as how well participants stick to the routine.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a standardized behavioral oral hygiene program using siwak (a chewing stick) delivered via a mobile app and practical training
What this could lead to
If effective, this siwak-based program could offer a culturally accepted alternative to toothbrushing for managing gingivitis.
What could go wrong
This is a small, short-term study in healthy young adults, so results may not apply to the general population or show long-term benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 66 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 24 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adults aged 18 - 24 years 2. Clinical dental students enrolled at one of the participating universities. 3. Participants with a maximum diagnosed with plaque-induced gingivitis according to the 2018 Classification of Periodontal and Peri-Implant Diseases and Conditions, without clinical attachment loss attributable to periodontitis. 4. Have adequate oral hygiene (ranging from good to fair; score from 0 to 1.9 according to Silness and Löe plaque index (1964) 5. Possess at least 28 natural teeth. 6. Able to understand study procedures and provide written informed consent. 7. Willing to comply with all study procedures, intervention instructions, and follow-up assessments. Exclusion Criteria: 1. Using braces and dental prosthesis. 2. Presence of systemic diseases known to influence oral and periodontal health 3. Use of antibiotics for the last 3 months or any medication or known to affect oral and periodontal tissues or salivary flow 4. Moderate or high dental caries risk 5. Severe tooth malposition that may interfere with plaque assessment or oral hygiene procedures 6. Participants presenting with moderate - severe dentin hypersensitivity 7. Participants with mucosa/ gingival trauma/recession and tooth wear 8. Pregnancy or breastfeeding 9. History of allergy or hypersensitivity to any material used in the study 10. Cognitive, psychiatric, or physical conditions that may impair compliance with study procedures

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Conditions

The condition(s) this trial relates to.

Bronchiolitis Obliterans Syndrome chronic gingivitis gingivitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gingivitis Gingivitis; chronic

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Dentistry, Universiti Kebangsaan Malaysia

    Kuala Lumpur, Kuala Lumpur, 50300, Malaysia

  • Faculty of Dentistry, Universiti Sains Islam Malaysia

    Kuala Lumpur, Kuala Lumpur, 55100, Malaysia

  • Faculty of Dentistry, Universiti Teknologi MARA

    Sungai Buloh, Selangor, 47000, Malaysia

  • Kulliyyah of Dentistry, International Islamic University Malaysia

    Kuantan, Pahang, 25200, Malaysia

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