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New hope for rare blood disorder when standard treatments fail

NCT ID NCT03933904

Summary

This study tests whether sirolimus, a medication that targets a specific cell pathway, can help adults with a rare blood disorder called idiopathic multicentric Castleman disease (iMCD) when standard treatments haven't worked. Participants take a daily pill for 12 months to see if it reduces symptoms like fatigue and fever while shrinking enlarged lymph nodes. The goal is to control the disease and improve quality of life for those who haven't responded to other therapies.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansas, 72205, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.