New hope for rare immune disorder patients who failed standard therapy

NCT ID NCT03933904

Summary

This study is testing a drug called sirolimus for adults with a rare immune system disorder called idiopathic multicentric Castleman disease (iMCD) who have not gotten better with standard treatments. Participants will take sirolimus daily for a year to see if it reduces symptoms like fatigue and fever and shrinks swollen lymph nodes. The goal is to see if this drug can help control the disease in patients who have few other options.

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Contacts and locations

Locations

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansas, 72205, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.