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Blood-Derived gel may boost bone growth in jaw surgery

NCT ID NCT07348198

Knowledge-focused Sponsor: Marmara University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 21 adults who needed sinus lift surgery on both sides of their upper jaw to get dental implants. On one side, they received a standard bone graft; on the other, the same graft plus platelet-rich fibrin (PRF) made from their own blood. Six months later, small bone samples were examined to see if PRF helped grow more new bone. The goal was to find out if adding PRF improves bone regeneration.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

21 people

The number who actually took part.

Started

Apr 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 70 years. * Patients requiring bilateral lateral maxillary sinus augmentation for dental implant placement. * Adequate residual alveolar bone height allowing for lateral sinus floor elevation. * Good general health (ASA I or II). * Ability to understand the study procedures and provide written informed consent. Exclusion Criteria: * Presence of systemic diseases affecting bone metabolism (e.g., uncontrolled diabetes, osteoporosis). * History of head and neck radiotherapy. * Use of medications known to affect bone healing (e.g., bisphosphonates, corticosteroids). * Active sinus pathology or chronic sinusitis. * Heavy smoking (\>10 cigarettes per day). * Pregnancy or lactation. * Poor oral hygiene or untreated periodontal disease.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Maxillary sinus augmentation Posterior maxillary atrophy

Contacts and locations

Locations

  • Marmara University

    Istanbul, Maltepe, 34854, Turkey (Türkiye)

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