New scanner aims to see heart arteries more clearly with less radiation
NCT ID NCT07411196
First seen Jun 27, 2026 · Last updated Sep 10, 2026 · Updated 2 times
Summary
This study will test a new type of CT scanner that uses silicon-based detectors to take detailed pictures of the heart. The goal is to see if it can provide clearer images of coronary arteries while using less radiation and contrast dye than current scanners. About 1,000 adults referred for a heart CT will be scanned with both the new and standard machines to compare image quality.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Photon-counting computed tomography (PCCT) device with silicon-based detectors
- What this could lead to
- If successful, this could lead to safer, more accurate heart scans with lower radiation and contrast doses, improving diagnosis of coronary artery disease.
- What could go wrong
- This is an early-stage device study with no treatment outcome; it may not consistently reduce radiation or improve image quality over current scanners.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,000 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2026
An estimate. Start dates often move.
- Expected to finish
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Apr 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Referred for clinically indicated cardiac CT * Age ≥18 years * Informed Consent signed by the subject Exclusion Criteria: * Known allergy to iodinated contrast * Pregnancy * Impaired renal function (eGFR\<30ml/min/1.73m2) * Any other common contraindication for routine cardiac CT or any other reason leading to the inability to successfully and completely perform routine cardiac CT with and without contrast-enhancement
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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