New sickle cell drug enters human trials – hope for better control
NCT ID NCT06481306
First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 26 times
Summary
This early-stage study tests a new medicine called BMS-986470 in about 184 people, including healthy volunteers and those with sickle cell disease. The main goal is to check safety and find the right dose, while also looking at how the drug works in the body and its early effects on the disease. It is not a cure, but aims to better control the condition.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Locations
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Assistance Publique Hôpitaux de Marseille - Hôpital de la Timone
RECRUITINGMarseille, 13385, France
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Boston Medical Center
RECRUITINGBoston, Massachusetts, 02118, United States
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Hôpital Universitaire Necker Enfants Malades
RECRUITINGParis, 75015, France
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Inova Schar Cancer Institute
RECRUITINGFairfax, Virginia, 22031, United States
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Institut de cancérologie Strasbourg Europe (ICANS)
RECRUITINGStrasbourg, Alsace, 67033, France
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King's College Hospital
RECRUITINGLondon, London, City of, SE5 9RL, United Kingdom
Contact
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Local Institution - 0001
ACTIVE_NOT_RECRUITINGLenexa, Kansas, 66219, United States
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Local Institution - 0005
NOT_YET_RECRUITINGLeeds, LS9 7TF, United Kingdom
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Local Institution - 0024
NOT_YET_RECRUITINGBoston, Massachusetts, 02114, United States
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Local Institution - 0032
NOT_YET_RECRUITINGPittsburgh, Pennsylvania, 15213, United States
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Local Institution - 0034
NOT_YET_RECRUITINGChicago, Illinois, 60612, United States
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Thomas Jefferson University - Medicine/GI and Hepatology
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact Phone: •••-•••-••••
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UCSF Benioff Children's Hospital Oakland
RECRUITINGOakland, California, 94609, United States
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University Hospitals Sussex NHS Foundation Trust
RECRUITINGEast Sussex, Brighton And Hove, BN2 1ES, United Kingdom
Contact Phone: •••-•••-••••
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35233, United States
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University of California San Diego - La Jolla
RECRUITINGLa Jolla, California, 92037, United States
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Virginia Commonwealth University (VCU) Medical Center
RECRUITINGRichmond, Virginia, 23298, United States
Contact Phone: •••-•••-••••
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Winship Cancer Institute of Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
Contact Phone: •••-•••-••••
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Yale-New Haven Hospital
RECRUITINGNew Haven, Connecticut, 06510, United States
Contact Phone: •••-•••-••••
Conditions
Explore the condition pages connected to this study.