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Scientists probe blood changes behind sickle cell pain attacks

NCT ID NCT03049475

First seen Sep 30, 2025 · Last updated May 20, 2026 · Updated 29 times

Summary

This study looked at what happens in the blood during painful attacks in people with sickle cell disease. Researchers compared blood samples taken during a pain crisis to samples taken when participants were feeling well. The goal was to learn more about the causes of pain and complications, not to test a new treatment. 99 adults with and without sickle cell disease took part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.