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Massive sickle cell study aims to unlock secrets of organ failure

NCT ID NCT02098863

First seen Oct 31, 2025 · Last updated Apr 30, 2026 · Updated 30 times

Summary

This study follows up to 10,000 people with sickle cell disease over many years, collecting health data and blood samples during regular clinic visits. The goal is to learn how the disease damages organs over time and how treatments like hydroxyurea affect long-term health. Participants can also join a sub-study to see how their genes affect their response to hydroxyurea. This is an observational study, not a test of new treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Illinois at OSF-Saint Francis Medical Center

    RECRUITING

    Peoria, Illinois, 61637, United States

    Contact Phone: •••-•••-••••

    Contact

  • Methodist Adult Comprehensive Sickle Cell Center

    RECRUITING

    Memphis, Tennessee, 38104, United States

    Contact

    Contact Phone: •••-•••-••••

  • Novant Health Hemby Children's Hospital

    RECRUITING

    Charlotte, North Carolina, 28204, United States

    Contact

    Contact Phone: •••-•••-••••

  • Our Lady of the Lake Regional Medical Center

    COMPLETED

    Baton Rouge, Louisiana, 70808, United States

  • Regional One Health, Diggs-Kraus Sickle Cell Center

    RECRUITING

    Memphis, Tennessee, 38103, United States

    Contact

    Contact Phone: •••-•••-••••

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.