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Could a few radiation sessions be enough for breast cancer?

NCT ID NCT07076485

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 32 times

Summary

This study is testing whether shorter courses of radiation therapy can work as well as standard treatment for people with breast cancer that has spread to lymph nodes. About 768 participants who have had surgery will receive either a very short (ultrahypofractionated) or moderately short radiation schedule. The goal is to see if these shorter treatments are safe and effective at preventing cancer from returning.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Banner MD Anderson Northern Colorado

    RECRUITING

    Loveland, Colorado, 80538, United States

    Contact Email: •••••@•••••

    Contact

  • Cooper Hospital University Medical Center

    RECRUITING

    Voorhees Township, New Jersey, 08103, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The University of Texas M. D. Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Texas Health Science Center at San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Radiation therapy (ultrahypofractionated or moderately hypofractionated)

What this could lead to

If successful, this could offer a shorter, more convenient radiation schedule for breast cancer patients, reducing treatment burden while maintaining effectiveness.

What could go wrong

This is a Phase 2 trial, so results are preliminary. Shorter radiation may not be as effective as standard schedules, and there is a risk of increased side effects or cancer recurrence.

Conditions

The condition(s) this trial relates to.

breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.