Could infants with fast heartbeat stop meds sooner?
NCT ID NCT04837261
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether infants with supraventricular tachycardia (SVT) can safely stop antiarrhythmic medication after just 4 months instead of longer. Researchers followed 107 infants aged 6 months or younger who were treated with drugs like propranolol or flecainide. The main goal was to see how many had a return of SVT after stopping medication early.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Propranolol, Flecainide, Amiodarone
- What this could lead to
- If successful, this could show that a shorter course of medication is safe and effective for infants with SVT, reducing drug exposure.
- What could go wrong
- This is an observational study, not a randomized trial, so results may be less reliable. The shorter course might lead to more recurrences of SVT.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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107 people
The number who actually took part.
- Started
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Apr 2021
- Finished
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Jan 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Infants age less than 6 months with SVT due to AVRT or AVNRT
- Ages
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Up to 6 months
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 6 months or less * Documented SVT due to AVRT or AVNRT Exclusion Criteria: * Age \> 6 months * Ectopic atrial tachycardia * Atrial flutter * Atrial fibrillation * Permanent junctional reciprocating tachycardia
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Central Finland Central Hospital
Jyväskylä, Central Finland, 40620, Finland
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Helsinki University Hospital
Helsinki, Uusimaa, 00029, Finland
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Hämeenlinna Central Hospital
Hämeenlinna, Kanta-Häme, 13530, Finland
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Kajaani Central Hospital
Kajaani, Kainuu, 87300, Finland
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Kokkola Central Hopsital
Kokkola, Keski-Pohjanmaa, 67200, Finland
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Kuopio University Hospital
Kuopio, Northern Savonia, 70029, Finland
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Kymenlaakso Central Hospital
Kotka, Region of Kymenlaakso, 48210, Finland
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Lahti Central Hospital
Lahti, Paijat-Hame Region, 15850, Finland
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Lapland Central Hospital
Rovaniemi, Lapland, 96101, Finland
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Mikkeli Central Hospital
Mikkeli, South Savo, 50100, Finland
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North Karelia Central Hospital
Joensuu, Pohjois-Karjala, 80210, Finland
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Oulu University Hospital
Oulu, North Ostrobothnia, 90220, Finland
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Sakunta Central Hospital
Pori, Satakunta, 28500, Finland
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Seinäjoki Central Hospital
Seinäjoki, South Ostrobothnia, 60220, Finland
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South Karelia Central Hospital
Lappeenranta, South Karelia Region, 53130, Finland
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Tampere University Hospital
Tampere, Pirkanmaa, 33520, Finland
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Turku University Hospital
Turku, Southwest, 20521, Finland
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Vaasa Central Hospital
Vaasa, Pohjanmaa, 65130, Finland
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