Could a nasal swab cure a racing heart? new study investigates
NCT ID NCT07617077
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a simple nasal swab to the standard Valsalva maneuver for stopping a common rapid heartbeat condition called supraventricular tachycardia (SVT). About 60 adults with SVT in the emergency room will be randomly assigned to one of the two methods. The goal is to see which approach restores a normal heart rhythm faster and more comfortably.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older * Electrocardiographically confirmed supraventricular tachycardia (SVT): narrow QRS complex (≤120 ms), regular rhythm, rapid ventricular rate, documented on 12-lead ECG or continuous cardiac monitoring * Hemodynamic stability, defined as ALL of the following simultaneously present: * Systolic blood pressure ≥90 mmHg * Diastolic blood pressure ≥60 mmHg * Alert and oriented mental status (GCS 15) * No signs of acute end-organ dysfunction * Ability and willingness to provide written informed consent Exclusion Criteria: * Age younger than 18 years * Pregnancy (known or suspected) * Inability to confirm SVT diagnosis by ECG criteria * Delta wave or pre-excitation pattern on ECG (Wolff-Parkinson-White syndrome or asymptomatic pre-excitation) - due to risk of ventricular fibrillation with vagal maneuvers * Wide QRS tachycardia (QRS ≥120 ms) where ventricular tachycardia cannot be excluded * Absolute contraindication to modified Valsalva maneuver (inability to assume supine position or passive leg elevation) * Contraindication to nasal swab (nasal surgery within 30 days, active epistaxis, visible nasal polyp or mass) * Hemodynamic instability requiring immediate synchronized cardioversion * Prior enrollment in this study (re-presentation with SVT) * Refusal to participate
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Marmara University Pendik Training and Research Hospital
RECRUITINGIstanbul, Pendik, 34899, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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