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One-Week radiation plus chemo: a new hope for endometrial cancer patients?

NCT ID NCT05691010

First seen Feb 04, 2026 · Last updated Jun 22, 2026 · Updated 16 times

Summary

This study is testing whether a short, 1-week course of radiation therapy combined with standard chemotherapy (carboplatin and paclitaxel) is practical for people with stage III endometrial cancer. The usual radiation takes 5 weeks, so this shorter schedule could be more convenient. The trial will enroll 28 participants to see if most can complete all 6 cycles of chemo without delays.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Memorial Sloan Kettering Basking Ridge (All protocol activities)

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Bergen (All protocol activities)

    RECRUITING

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Commack (All protocol activities)

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Monmouth (All protocol activities)

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Nassau (All protocol activities)

    RECRUITING

    Uniondale, New York, 11553, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Westchester (All protocol activities)

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

carboplatin, paclitaxel, and intensity-modulated radiation therapy (IMRT)

What this could lead to

If successful, this could offer a more convenient treatment option for stage III endometrial cancer by shortening radiation from 5 weeks to 1 week.

What could go wrong

This is a very early feasibility study with only 28 participants. It is not designed to prove the treatment works better than standard care, and side effects from combining chemo and radiation are possible.

Conditions

The condition(s) this trial relates to.

endometrial cancer endometrial carcinoma endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.