Shame may be a key warning sign for suicide in borderline personality disorder
NCT ID NCT03994510
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study follows 688 adults with borderline personality disorder (BPD) for 5 years to see if feeling shame can predict suicide attempts. Researchers will also look for biological markers and protective treatments. No new drug or therapy is being tested—this is purely an observation study to better understand the link between shame and suicidal behavior.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors identify who is at higher risk for suicide attempts based on feelings of shame, leading to better prevention strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly improve symptoms, and results may not apply to everyone with borderline personality disorder.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 688 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2020
- Expected to finish
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Sep 2031
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: * To be over 18 * Clinical diagnosis of BPD using the SCID II (Structured Clinical Interview for DSM-IV-Text Reviewed Axis II Personality Disorders) * Having signed the informed consent * Able to understand the nature, the purpose and the methodology of the study * Able to understand and perform the clinical evaluations Exclusion criteria: * Deprived of liberty (by judicial or administrative decision) * Protected by law (guardianship) * Exclusion period in relation to another protocol * Not affiliated to a social security scheme
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University Hospital of Montpellier
RECRUITINGMontpellier, Hérault, 34295, France
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Other studies related to the condition(s) this trial covers.
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- Couples therapy takes on suicide: a new approach targets both emotions and relationships
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