Which sterilization method is better for your sex life? new study compares two techniques
NCT ID NCT05910385
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed trial looked at 140 women who had their tubes tied (tubal ligation) to see if the surgical method affects sexual quality of life after 6 months. One group had standard abdominal laparoscopy, the other had a newer vaginal approach called vNOTES. Participants filled out a questionnaire about their sexual function before and after surgery. The goal was to see if vNOTES is at least as good as laparoscopy in preserving sexual satisfaction.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help women choose a sterilization method that better preserves sexual satisfaction.
- What could go wrong
- This is a small, completed study (140 participants) comparing two surgical techniques, not testing a new treatment. Results may not apply to all women or settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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140 people
The number who actually took part.
- Started
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May 2022
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult woman, eligible for tubal ligation by total salpingectomy or tubal section coagulation, sexually active at the time of inclusion * Able to give informed consent to participate in research * Affiliated to a social security system. Exclusion Criteria: * Current pregnancy or breastfeeding * Indications of another concomitant surgical procedure (other than procedure on the appendix) * History of upper genital infection * Proven or suspected rectovaginal endometriosis on clinical examination * History of rectal surgery * Virgin patient * Any concomitant pathology deemed incompatible with the study. * Uncured COVID or SARS-COv2 positivity dated less than 3 days prior to surgery. * Protected adult patient, under guardianship or curatorship * Patients not affiliated to the social security system * Patients who do not speak French * Patients under legal protection * Refusal to participate.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CH d'Issoire
Issoire, 63500, France
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CHU de Clermont-Ferrand
Clermont-Ferrand, 63000, France
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