Muscle recovery differs between sexes, new study reveals
NCT ID NCT04151901
First seen Feb 01, 2026 · Last updated Jun 23, 2026 · Updated 23 times
Summary
This study looks at how middle-aged men and women lose muscle after a week of not using one leg, and how they recover with exercise. Researchers will measure muscle strength, size, and genetic activity to find sex-specific differences. The goal is to learn more so future treatments can be tailored to each sex.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University of Texas Health Science Center at San Antonio
San Antonio, Texas, 78229, United States
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University of Texas Medical Branch
Galveston, Texas, 77555, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Resistance exercise rehabilitation and walking-based rehabilitation
What this could lead to
If successful, this could help design better, sex-specific rehabilitation programs for middle-aged people after periods of inactivity.
What could go wrong
This is a small, early-phase study with only 37 participants, so results may not apply to everyone. It focuses on understanding mechanisms, not on testing a new treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.