Kidney disease and Women's heart risk: hormones may hold the key
NCT ID NCT05471518
First seen Sep 30, 2025 · Last updated Jun 23, 2026 · Updated 42 times
Summary
This study looked at how sex hormones, especially estradiol, affect blood vessel function in women with chronic kidney disease (CKD). Researchers compared pre- and post-menopausal women with CKD to healthy women of similar ages. The goal was to understand why women with CKD have a higher risk of heart disease and whether hormones play a role. No treatments were given—this was an observational study to gather information.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University of Colorado Anschutz Medical Campus
Aurora, Colorado, 80045, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this research could help explain why women with CKD have higher heart disease risk and point toward hormone-based treatments to protect their blood vessels.
What could go wrong
This is a small, completed observational study (51 participants) that only measures associations, not causes. The findings may not apply to all women with CKD or lead directly to treatments.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.