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Promising drug targets severe hunger in rare genetic disorder

NCT ID NCT06772597

First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 26 times

Summary

This study tests a daily injection called setmelanotide in 18 people aged 6 to 65 with Prader-Willi syndrome, a condition causing severe obesity and constant hunger. The goal is to see if the drug safely reduces body weight and controls appetite over 52 weeks. Participants must have a high BMI and agree to use contraception.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Florida

    Gainesville, Florida, 32610-0296, United States

Conditions

Explore the condition pages connected to this study.