Could simple blood tests spot sepsis sooner?
NCT ID NCT07537179
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study examined whether certain blood cell measurements—monocyte distribution and ratios of white blood cells—can help detect sepsis in intensive care patients. Researchers followed 120 adults in the ICU, comparing these new markers with standard infection tests. The goal was to see if these simple blood counts could aid in faster or more accurate sepsis diagnosis.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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120 people
The number who actually took part.
- Started
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Oct 2022
- Finished
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Jan 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of three groups: Group I: Control group - patients over 18 years of age, classified as ASA I-II, with no infection, who applied to the anesthesia outpatient clinic and did not meet any exclusion criteria; Group II: patients who were admitted to the intensive care unit for reasons other than sepsis and subsequently developed sepsis; Group III: patients admitted to the intensive care unit with a primary diagnosis of sepsis.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients monitored in the intensive care unit for at least 24 hours * Age over 18 years * Diagnosis of sepsis or septic shock Exclusion Criteria: * Patients with hematological diseases * Patients who have undergone organ or bone marrow transplantation * Patients diagnosed with AIDS * Patients receiving immunosuppressive therapy for any reason * Patients with chronic renal failure * Patients with liver failure not related to sepsis * Patients admitted due to intoxication * Patients with intracranial pathologies (e.g., mass, hemorrhage) that may lead to morbidity due to volume loading
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Sivas Cumhuriyet University
Sivas, Sivas, 58140, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Two cheap blood ratios put to the test as sepsis death predictors
- Can a computer model speed up sepsis blood tests?
- Stem cells put to the test against Sepsis's immune chaos
- Can the immune system reveal who will suffer kidney injury after sepsis?
- A routine calcium reading could reveal how sick a sepsis patient really is