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New combo therapy trial hopes to tame tough cancers

NCT ID NCT06545682

First seen Oct 31, 2025 · Last updated Apr 30, 2026 · Updated 21 times

Summary

This early-phase study tests the safety of combining two drugs, alpelisib and pembrolizumab, in people with advanced breast cancer or melanoma that has spread. About 50 adults whose cancer has not responded to standard treatments will receive the combination to find the best dose and monitor side effects. The goal is to control the disease, not to cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.