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Liver study measures drug levels in PBC patients

NCT ID NCT04950764

First seen May 20, 2026 · Last updated May 24, 2026 · Updated 1 time

Summary

This study looked at how the body handles the drug seladelpar in 24 adults with primary biliary cholangitis (PBC) and varying degrees of liver impairment. Researchers measured drug levels in the blood and urine to see how liver function affects the drug's breakdown. The goal was to gather information, not to treat the disease.

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Contacts and locations

Locations

  • American Research Corporation

    San Antonio, Texas, 78215, United States

  • Arizona Liver Health

    Chandler, Arizona, 85224, United States

  • Henry Ford Health System

    Novi, Michigan, 48377, United States

  • Hospital General Universitario Gregorio Maran

    Madrid, 28007, Spain

  • Inje University Busan Paik Hospital

    Busan, South Korea

  • Kings College Hospital

    London, SE5 9RS, United Kingdom

  • Kyungpook National University Hospital

    Daegu, 41944, South Korea

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mercy Medical Center

    Baltimore, Maryland, 21202, United States

  • NIHR BRC Centre for Liver and Gastrointestinal Research Birmingham

    Birmingham, B15 2GW, United Kingdom

  • Pinnacle Clinical Research- SA

    San Antonio, Texas, 78229, United States

  • Pusan National University Hospital

    Busan, 49241, South Korea

  • Seoul National University Hospital

    Seoul, 3080, South Korea

  • Severance Hospital Yonsei University Health System

    Seoul, 3722, South Korea

  • Southern Therapy and Advanced Research LLC

    Jackson, Mississippi, 39216, United States

  • The Liver Institute at Methodist Dallas Medical Center

    Dallas, Texas, 75203, United States

  • The Royal Free London NHS Foundation Trust

    London, NW2 2QG, United Kingdom

  • University of California Davis

    Sacramento, California, 95817, United States

  • University of Colorado Anschutz

    Aurora, Colorado, 80045, United States

  • Weill Medical College of Cornell University

    New York, New York, 10021, United States

Conditions

Explore the condition pages connected to this study.