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Can an MRI predict diabetes complications?

NCT ID NCT05057403

Knowledge-focused Sponsor: Perspectum Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will use a special MRI scan to look at the health of multiple organs in 1,000 adults with type 2 diabetes who have not had heart problems. Researchers want to see if these scans can predict future heart attacks, strokes, or kidney disease over five years. The goal is to find better ways to catch complications early.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify type 2 diabetes patients at higher risk for heart or kidney disease earlier, leading to better prevention strategies.
What could go wrong
This is an observational study, not a treatment trial. It may not find strong links between MRI results and future health events, or the findings may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2022

Expected to finish

Jun 2034

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult participants, aged 18 years of age and over with type 2 diabetes lacking history of cardiovascular disease. Recruitment will be carried out from patients identified following diabetes or diabetic retinopathy diagnoses or via self-referral. 1. Diabetes referral appointments 2. Diabetic retinopathy referral appointments 3. Primary care and diabetes clinics - including GP practices 4. Participant Identification Centres 5. Diabetes Eye Screening Programmes (DESP)

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female at least 18 years of age and diagnosed with type 2 diabetes, with or without diabetic retinopathy. * Participant willing and able to give informed consent for participation in the study. Exclusion Criteria: In 12 months prior to consent, evidence of existing cardiovascular event defined as at least one of: * myocardial infarction * ischaemic stroke * hospital admission/discharge for unstable angina * heart surgery * unstable angina * transient ischemic attack * The participant may not enter the study if they have any contraindication to magnetic resonance imaging (standard MR exclusion criteria including pregnancy, extensive tattoos, pacemaker, shrapnel injury, severe claustrophobia). * Patients with known autoimmune hepatitis, viral hepatitis, Wilson's disease or known significant structural renal tract abnormality. * Patients with known alcohol dependency. * Any other cause, including a significant disease or disorder which, in the opinion of the investigator, may either put the participant at risk because of participation in the study, or may influence the participant's ability to participate in the study

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE2 diabetes

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    12 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Eynsham Medical Centre

    RECRUITING

    Eynsham, Oxfordshire, OX29 4QB, United Kingdom

  • Hedena Health

    RECRUITING

    Oxford, OX3 9JA, United Kingdom

  • Moorfields Eye Hospital NHS Foundation Trust

    ENROLLING_BY_INVITATION

    London, United Kingdom

  • Oxford Community Diagnostic centre

    RECRUITING

    Oxford, OX42LL, United Kingdom

  • St Bartholomew and Hollow Way Medical Practice

    RECRUITING

    Oxford, OX4 1XB, United Kingdom

  • Swansea Bay University Health Board

    NOT_YET_RECRUITING

    Baglan, Swansea, SA12 7BR, United Kingdom

  • The House Partnership

    RECRUITING

    Redhill, Surrey, RH1 1EB, United Kingdom

  • The Manor Group

    RECRUITING

    Oxford, OX3 9BP, United Kingdom

  • University Hospitals of Liverpool Group

    RECRUITING

    Liverpool, L9 7AL, United Kingdom

  • White Horse Medical Practice

    RECRUITING

    Farringdon, Oxfordshire, SN7 7YU, United Kingdom

  • Windrush Medical Practice

    RECRUITING

    Witney, Oxfordshire, OX26 6JS, United Kingdom

  • Woodlands Medical Centre

    RECRUITING

    Didcot, Oxfordshire, OX11 0BB, United Kingdom

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